The Taranto station is the main railway station for both freight and passenger services in the city of Taranto.

The National Archaeological Museum of Taranto (MArTA) displays one of the largest collections of artifacts dating back to the Magna Graecia era, including the famous golds of Taranto.

The Amati Palace in Taranto is one of the most prestigious buildings in the Old Town of the city.

The Latagliata Palace in Taranto is a building that houses the municipal offices in the Old Town of the city.

MUDI - Diocesan Museum of Sacred Art or Mu.di. is housed in the premises of the sixteenth-century Archbishop's Seminary of Taranto in the Old City. Considered one of the largest museum structures in Italy, MUDI is set up in the renovated structure of the former Archbishop's Seminary of Taranto, in the heart of the old town, just a few steps from the Cathedral of San Cataldo.

The Palazzo Pantaleo in Taranto is an 18th-century building owned by the Municipality. From 2000 to 2007, it housed some collections from the National Archaeological Museum of Taranto in the Old Town. Currently, it is the headquarters of the Alfredo Majorano Ethnographic Museum.

The Aragonese Castle of Taranto, also known as Sant'Angelo Castle, is one of the most fascinating architectural and historical icons of Puglia. It stands at the tip of the island of the old town, in a strategic position between the Mar Grande and the Mar Piccolo, guarding the navigable channel that connects the two seas. Today it is one of the most beloved destinations for tourists and history enthusiasts.

The church of San Domenico (formerly the church of San Pietro Imperiale) is a Romanesque-Gothic style church located on the western side of the historic center (Old Town) of Taranto, whose construction was completed around 1360.